Time is a crucial factor for routine cytogenetic diagnostics, as there is a strong
demand to shorten case turnover times; this is why we designed Ikaros to be the
fastest karyotyping system available. To achieve this goal, we have created a
remarkably streamlined software architecture, direct access to all functions with
minimal user interaction, and unique image acquisition and enhancement tools.
It is more efficient to actually use a tool than to lose time learning how to handle it.
Working with Ikaros is extremely easy, and therefore, training times can be
reduced to an absolute minimum. Generally, it takes only a few minutes until the
first karyogram is prepared, and the skills required to handle Ikaros can be easily
shared among colleagues and new members of the workgroup.
Metaphase images acquired with Ikaros excel in quality, which is due to the unique
combination of a high-resolution CCD camera ( ) and a
variety of dedicated software tools. The latter include automated contrast
adjustment, a focusing aid to help find the best focus image, and a convenient, yet
comprehensive banding enhancement filter, which is simply applied with the
mouse.
Image Acquisition
Image Enhancement
Chromosome Separation
Karyotyping
One-click image acquisition of G-, R-, Q-, and DAPI-banded metaphases,
or of metaphases with other staining patterns
Focusing aid for automated best focus acquisition
Powerful image filter tools for banding enhancement
Unlimited undo, processing steps list, and any-time access to original image
Automated, semi-automated, and manual separation of chromosomes
Separation of chromosome clusters with the chromosome brush tool
Image zoom function on the mouse wheel
Automated and manual assignment of chromosomes
Classification of chromosomes in the metaphase
Ideograms (ISCN 2009) with different resolutions, flexible annotation function,
and karyogram form editor
Karyogram comparison and partial karyograms with aberrant chromosomes