XCyting Multiclor Chromosome Banding (mBAND) Kits

MetaSystems also offers probe kits for high resolution multicolor chromosome banding (mBAND), and chromosome paints for rat and mouse chromosomes, which are currently not published here. However, this page will be regularly updated, so please come back later. Meanwhile please contact probes@metasystems.de  for details on unlisted probe kits.
Fluorescence in situ hybridization (FISH) has become a major tool for research in human chromosomes, tumor cytogenetics and diagnostics. Its is routinely applied in genetics and allows nearly unlimited and targeted visualization of genomic DNA using either metaphase spreads, interphase nuclei, tissue sections, or living cells. FISH applications are particularly important for the detection of structural rearrangements such as microdeletions, translocations, inversions, and insertions, as well as for identification of marker chromosomes, characterization of chromosome breakpoints, and prenatal aneuploidy testing. The clinical impact of FISH is huge especially in the diagnosis, prognosis and therapy of haematological diseases. Here, FISH plays a central role in combination with classic chromosome banding analysis to rapidly detect and to verify specific aberrations.

• XCyting Multiclor Chromosome Banding (mBAND) Kits